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Department of Statistics

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Cliff Pereira

Faculty Research Associate
Department of Statistics
Portrait image of cliff pereira.

Connect with Cliff

Weniger Hall, Rm# 209

Cliff Pereira

Faculty Research Associate
Department of Statistics

Current Research Interests

  • Applications of statistics in biology.
  • Design and analysis of Experiments.
  • Mixed models, specifically models for complex multi-level designs and issues in extending linear mixed model results to generalized linear mixed models and other non-linear mixed models. Permutation tests for sparse data.
  • Statistical Consulting.

Instructional & Departmental Activities

  • Director, Consulting Practicum (ST509C) 1990 to Present
  • Advanced Experimental Design (ST555) 1990 to Present

Professional Societies/Responsibilities/Honors

  • Chair of organizing committee for Justus F. Seely Memorial Conference on Linear Models (2002-2003).
  • Secretary-Treasurer (1998-1999), Section on Statistical Consulting, American Statistical Association (ASA).
  • ASA Council of Chapters, Chapter Service Recognition Award, 1994.
  • Secretary-Treasurer (1986-87), Vice-President (1987-88), President (1988-1989), Council Representative (1989-1990), Oregon Chapter, ASA.
  • Member: American Statistical Association, Biometrics Society

Other Interests

Music (from folk through jazz to classical) and outdoor activities (from gardening through birding to backpacking).

Publications

  • Yu Z, Loehr CV, Fischer KA, Louderback MA, Krueger SK, Dashwood RH, Kerkvliet NI, Pereira CB, Jennings-Gee J, Dance ST, Miller MS, Bailey GS, Williams DE (2006). In Utero exposure of mice to dibenzo[a,l]pyrene produces lymphoma in the offspring: role of the aryl hydrocarbon receptor. Cancer Research 66, 755–762
  • Reimers MJ, Laud JK, Pereira CB, Giovanini J, Tanguay RL (2006). Ethanol-dependent toxicity in zebrafish is partially attenuated by antioxidants. Neurotoxicol Teratol 28, 497-508.
  • Tilton SC, Givan SA, Pereira CB, Bailey GS, Williams DE (2006). Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17beta-estradiol and beta-naphthoflavone in rainbow trout. Toxicol Sci. 90(1):61-72.
  • Yu Z, Mahadevan B, Loehr CB, Fischer KA, Louderback MA, Krueger SK, Pereira CB, Albershardt DJ, Baird WM, Bailey GS, Williams DE (2006). Indole-3-carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by the polycyclic aromatic hydrocarbon, dibenzo[a,l]pyrene. Carcinogenesis 27(10):2116-2123.
  • Krueger SD, Siddens LK, Henderson MC, VanDyke JE, Karplus PA, Pereira CB, Williams DE (2006). C-Terminal truncation of rabbit flavin-containing monooxygenase isoform 2 enhances solubility. Arch Biochem Biophys 450(2): 149-156.
  • Mahadevan B, Marston CP, Luch A, Dashwood W-M, Brooks E, Pereira C, Doehmer J, Baird WM (2006) Competitive inhibition of carcinogen-activating CYP1A1 and CYP1B1 enzymes by a standardized complex mixture of PAH extracted from coal tar. Int . J. Cancer 120(6):1161-1168.
  • Pratt MM, Reddy AP, Hendricks JD, Pereira C, Kenslar TW, Bailey GS (2007). The importance of carcinogen dose in chemoprevention studies: quantitative interrelationships between, dibenzo[a,l]pyrene dose, chlorophyllin dose, target organ DNA adduct biomarkers, and final tumor outcome. Carcinogenesis 28(3):611-624; doi:10.1093/carcin/bgl174.
  • Tilton SC, Hendricks JD, Orner GA, Pereira CB, Bailey GS, Williams DE (2007). Gene expression analysis during tumor enhancement by the dietary phytochemical, 3,3''-diindolylmethane, in rainbow trout. Carcinogenesis 28(7):1589-1598; doi:10.1093/carcin/bgm017.
  • Carter O, Dashwood RH, Wang R, Orner GA, Fischer KA, Lohr CV, Pereira CB, Bailey GS, Williams DE (2007) Comparison of White Tea, Green Tea, Epigallocatechin-3-Gallate, and Caffeine as Inhibitors of PhIP-Induced Colonic Aberrant Crypts. Nutrition and Cancer 58(1):60-65.
  • Courter LA, Musafia-Jeknic T, Fischer K, Bildfell R, Giovanini J, Pereira C, Baird WM (2007) Urban Dust Particulate Matter Alters PAH-Induced Carcinogenesis by Inhibition of CYP1A1 and CYP1B1. Toxicol Sci 95(1):63-73.
  • Courter LA, Pereira C, Baird WM (2007) Diesel Exhaust Influences Carcinogenic PAH-Induced Genotoxicity and Gene Expression in Human Breast Epithelial Cells in Culture. Mutat Res 625(1-2):72-82.
  • Simonich MT, Egner PA, Roebuck BD, Orner GA, Jubert C, Pereira C, Groopman JD, Kensler TW, Dashwood RH, Williams DE, Bailey GS (2007) Natural chlorophyll inhibits aflatoxin B1-induced multi-organ carcinogenesis in the rat. Carcinogenesis 28(6):1294-1302; doi:10.1093/carcin/bgm027
  • Courter L, Luch A, Musafia-Jeknic T, Arlt V, Fischer K, Bildfell R, Pereira C, Phillips D, Poirier M, Baird W (2008). The influence of diesel exhaust on polycyclic aromatic hydrocarbon-induced DNA damage, gene expression, and tumor initiation in Sencar mice in vivo Cancer Letters 265(1): 135-147.
  • Wang R, Dashwood WM, Lohr CV, Fischer KA, Pereira CB, Louderback M, Nakagama H, Bailey GS, Williams DE, Dashwood RH (2008). Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat. Carcinogenesis 29(4): 834-9.
  • Simonich MT, McQuistan T, Jubert C, Pereira C, Hendricks JD, Schimerlik M, Zhu B, Dashwood RH, Williams DE, Bailey GS (2008). Low-dose dietary chlorophyll inhibits multi-organ carcinogenesis in the rainbow trout. Food Chem Toxicol 46(3): 1014-24.
  • Castro DJ, Baird WM, Pereira CB, Giovanini J, Lohr CV, Fischer KA, Yu Z, Gonzalez FJ, Krueger SK, Williams DE (2008) Fetal Mouse Cyp1b1 and Transplacental Carcinogenesis from Maternal Exposure to Dibenzo(a,l)pyrene Cancer Prev Res 1: 128-134.
  • Castro DJ, Yu Z, Lohr CV, Giovanini J, Fischer KA, Orner GA, Dashwood RH, Williams DE (2008) Chemoprevention of Dibenzo[a,l]pyrene Transplacental Carcinogenesis in Mice Born to Mothers Administered Green Tea: Primary Role of Caffeine. Carcinogenesis 29:1581-1586.
  • Wollenweber E, Fischer R, Dorr M, Irvine K, Pereira CB, Stevens JF (2008) Chemodiversity of exudate flavonoids in Cassinia and Ozothamnus (Asteraceae, Gnaphalieae) Z. Naturforsch. 63c, 731-739
  • Tilton SC, Orner GA, Benninghoff AD, Carpenter HM, Hendricks JD, Pereira CB and Williams DE (2008) Genomic Profiling Reveals an Alternate Mechanism for Hepatic Tumor Promotion by Perfluorooctanoic Acid in Rainbow Trout. Environ Health Perspect 116(8): 1047–1055.
  • Bailey GS, Reddy AP, Pereira CB, Harttig U, Baird W, Spitsbergen JM, Hendricks JD, Orner GA, Williams DE and Swenberg JA (2009) Nonlinear Cancer Response at Ultralow Dose: A 40800-Animal ED001 Tumor and Biomarker Study. Chem. Res. Toxicol 22(7): 1264–1276
  • Jubert C, Mata J, Bench G, Dashwood R, Pereira C, Tracewell W, Turteltaub K, Williams D and Bailey G (2009) Effects of chlorophyll and chlorophyllin on low-dose aflatoxin B1 pharmacokinetics in human volunteers: A pilot study. Cancer Prevention Research 2(12): 1015-1022
  • Bailey GS, Orner GA, Pereira CB and Swenberg JA (2009). Response to the Waddell, et al. Letter. Chem. Res. Toxicol 22(9): 1493-1494.
  • McQuistan TJ, Simonich MT, Pratt MM, Pereira CB, Hendricks JD, Dashwood RH, Williams DE and GS Bailey (2012). Cancer chemoprevention by dietary chlorphylls: A 12000-animal dose-dose matrix biomarker and tumor study. Jour Food and Chem Toxicol 50(2):341-352.
  • Siddens LK, Larin A, Krueger SK, Bradfield CA, Waters KM, Tilton SC, Pereira CB, Lohr CV, Arlt VM, Phillips DH, Williams DE and Baird WM (2012). Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse. Toxicology and Applied Pharmacology doi: 10.1016/j.taap.2012.08.014